Structure-function relationship of nucleic acids and their complexes
Dr. Sabine Schneider
Department of Chemistry, Center for Nanoscience (CeNS), Ludwig-Maximilians-Universität, München
Nucleic acids within our cells are more than information carrier in the flow of genetic information in biological systems. They fulfil very diverse functions in numerous cellular processes, such as the regulation of gene expression and cell signalling, they mediate protein interactions, control enzyme activity, can catalyse chemical reactions and are crucial for cellular immunity. My research group is interested in the molecular mechanisms and how nucleic acids structure and chemical modification impact on their cellular roles. Particular we are interested on how non-coding RNAs programm protein function and the role of their chemical modification on gene regulatory processes.